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Emerging data on the effect of dopamine replacement therapy on gastrointestinal symptoms, across a range of conditions from neurodegenerative disease to inflammatory bowel disease, are also explored

Orlistat (Xenical, alli) does not affect heart rate as it works by blocking fat absorption in the gut rather than through systemic stimulation

Moreover, in the Trial to Evaluate Cardiovascular and Other Long-term Outcomes with Semaglutide in Subjects with Type 2 Diabetes and Peptide Innovation for Early Diabetes Treatment trials, slower eGFR decline or Kidney Disease Improving Global Outcomes risk improvement was most evident in lower eGFR subgroups, pointing to kidney protection with advancing CKD

Stool Softeners (e.g., Docusate Sodium/Colace): How they work: Increase the amount of water and fat the stool absorbs, making it softer and easier to pass